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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR35
All Species:
35.45
Human Site:
Y480
Identified Species:
70.91
UniProt:
Q9P2L0
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2L0
NP_001006658.1
1181
133547
Y480
K
E
G
R
E
R
I
Y
H
V
D
D
T
P
S
Chimpanzee
Pan troglodytes
XP_515315
1273
143538
Y572
K
E
G
R
E
R
I
Y
H
V
D
D
T
P
S
Rhesus Macaque
Macaca mulatta
XP_001107482
1296
146192
Y595
K
E
G
R
E
R
I
Y
H
V
D
D
T
P
S
Dog
Lupus familis
XP_532884
1356
153148
Y480
K
E
G
R
E
R
I
Y
H
I
D
D
T
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BND3
1181
133947
Y480
K
E
G
R
E
R
I
Y
H
V
D
D
V
P
S
Rat
Rattus norvegicus
NP_001092810
1170
132761
Y469
K
E
G
R
E
R
I
Y
H
V
D
D
V
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511461
679
76765
Q45
P
S
N
L
S
M
N
Q
T
L
E
G
H
S
G
Chicken
Gallus gallus
XP_419970
1197
135555
Y499
K
E
G
R
E
R
I
Y
H
I
D
D
T
P
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001139061
1203
136070
Y500
K
E
G
R
E
R
V
Y
H
I
D
D
S
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647653
1205
135183
K487
L
H
N
V
K
A
R
K
E
K
R
F
H
I
D
Honey Bee
Apis mellifera
XP_394812
1185
134241
L485
V
T
E
V
I
Q
D
L
D
K
D
R
S
F
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783217
1209
136043
Y497
K
D
S
R
E
K
V
Y
H
V
D
D
T
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.3
89.8
82
N.A.
92.2
91.7
N.A.
51.1
84.4
N.A.
78
N.A.
47.2
51.9
N.A.
66.3
Protein Similarity:
100
92.6
90.6
84.7
N.A.
96.7
96
N.A.
54.4
92.2
N.A.
88.4
N.A.
64.9
70.6
N.A.
80.5
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
0
93.3
N.A.
80
N.A.
0
6.6
N.A.
73.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
13.3
100
N.A.
100
N.A.
6.6
20
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
9
0
9
0
84
75
0
0
9
% D
% Glu:
0
67
9
0
75
0
0
0
9
0
9
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
0
% F
% Gly:
0
0
67
0
0
0
0
0
0
0
0
9
0
0
9
% G
% His:
0
9
0
0
0
0
0
0
75
0
0
0
17
0
0
% H
% Ile:
0
0
0
0
9
0
59
0
0
25
0
0
0
9
0
% I
% Lys:
75
0
0
0
9
9
0
9
0
17
0
0
0
0
0
% K
% Leu:
9
0
0
9
0
0
0
9
0
9
0
0
0
0
0
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
17
0
0
0
9
0
0
0
0
0
0
0
0
% N
% Pro:
9
0
0
0
0
0
0
0
0
0
0
0
0
75
0
% P
% Gln:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
75
0
67
9
0
0
0
9
9
0
0
0
% R
% Ser:
0
9
9
0
9
0
0
0
0
0
0
0
17
9
75
% S
% Thr:
0
9
0
0
0
0
0
0
9
0
0
0
50
0
0
% T
% Val:
9
0
0
17
0
0
17
0
0
50
0
0
17
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
75
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _